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CD46 antibody (AA 317-343)

CD46 Reactivity: Human WB, FACS, IF, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030405
  • Target See all CD46 Antibodies
    CD46
    Binding Specificity
    • 16
    • 13
    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 317-343
    Reactivity
    • 117
    • 39
    • 20
    • 10
    • 10
    • 1
    Human
    Host
    • 84
    • 53
    • 2
    Rabbit
    Clonality
    • 72
    • 67
    Polyclonal
    Conjugate
    • 52
    • 18
    • 16
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD46 antibody is un-conjugated
    Application
    • 91
    • 79
    • 42
    • 39
    • 32
    • 19
    • 14
    • 14
    • 14
    • 10
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 317-343 from the human protein was used as the immunogen for this CD46 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CD46 Primary Antibody
  • Application Notes
    Titration of the CD46 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the CD46 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    CD46
    Alternative Name
    CD46 (CD46 Products)
    Synonyms
    AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
    Background
    CD46 is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system.
    UniProt
    P15529
    Pathways
    Regulation of Actin Filament Polymerization
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