TM6SF2 antibody (C-Term)

Catalog No. ABIN2500373

This Rabbit Polyclonal antibody specifically detects TM6SF2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit and Cow. It has been mentioned in 2+ publications

Quick Overview for TM6SF2 antibody (C-Term) (ABIN2500373)

Target: TM6SF2 (Transmembrane 6 Superfamily Member 2 (TM6SF2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TM6SF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TM6SF2 Antibody

Binding Specificity: C-Term

Sequence: FFTLFRGLVV LDCPTDACFV YIYQYEPYLR DPVAYPKVQM LMYMFYVLPF

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 75%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TM6SF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TM6SF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TM6SF2 antibody (ABIN2500373)

Sookoian, Castaño, Scian, Mallardi, Fernández Gianotti, Burgueño, San Martino, Pirola: "Genetic variation in transmembrane 6 superfamily member 2 and the risk of nonalcoholic fatty liver disease and histological disease severity." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 2, pp. 515-25, (2015) (PubMed).

Holmen, Zhang, Fan, Hovelson, Schmidt, Zhou, Guo, Zhang, Langhammer, Løchen, Ganesh, Vatten, Skorpen, Dalen, Zhang, Pennathur, Chen, Platou, Mathiesen, Wilsgaard, Njølstad, Boehnke, Chen, Abecasis et al.: "Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk. ..." in: Nature genetics, Vol. 46, Issue 4, pp. 345-51, (2014) (PubMed).

Target Details for TM6SF2

Target: TM6SF2 (Transmembrane 6 Superfamily Member 2 (TM6SF2))

Alternative Name: TM6SF2

Background: The function of this protein remains unknown.
Protein Size: 350

Molecular Weight: 38 kDa

Gene ID: 53345