TM6SF2 antibody (C-Term)

Catalog No. ABIN2781848

Product Details anti-TM6SF2 Antibody

Target: TM6SF2 (Transmembrane 6 Superfamily Member 2 (TM6SF2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TM6SF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FFTLFRGLVV LDCPTDACFV YIYQYEPYLR DPVAYPKVQM LMYMFYVLPF

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 75%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TM6SF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TM6SF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TM6SF2 antibody (ABIN2781848)

Sookoian, Castaño, Scian, Mallardi, Fernández Gianotti, Burgueño, San Martino, Pirola: "Genetic variation in transmembrane 6 superfamily member 2 and the risk of nonalcoholic fatty liver disease and histological disease severity." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 2, pp. 515-25, (2015) (PubMed).

Holmen, Zhang, Fan, Hovelson, Schmidt, Zhou, Guo, Zhang, Langhammer, Løchen, Ganesh, Vatten, Skorpen, Dalen, Zhang, Pennathur, Chen, Platou, Mathiesen, Wilsgaard, Njølstad, Boehnke, Chen, Abecasis et al.: "Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk. ..." in: Nature genetics, Vol. 46, Issue 4, pp. 345-51, (2014) (PubMed).

Target Details for TM6SF2

Target: TM6SF2 (Transmembrane 6 Superfamily Member 2 (TM6SF2))

Alternative Name: TM6SF2 (TM6SF2 Products)

Synonyms: transmembrane 6 superfamily member 2 antibody, TM6SF2 antibody, tm6sf2 antibody, Tm6sf2 antibody

Background: The function of this protein remains unknown.
Protein Size: 350

Molecular Weight: 38 kDa

Gene ID: 53345