TNFRSF10B antibody (Biotin)

Catalog No. ABIN2629393

Product Details anti-TNFRSF10B Antibody (Biotin)

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF10B antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)

Specificity: Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4.

Purification: Protein G purified from tissue culture supernatant

Immunogen: Recombinant human TRAIL-R2 (DR5).

Type of Immunogen: Recombinant protein

Clone: HS201

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func, ICC, IP

Usage: Functional Application - Inhibition (blocks TRAIL-R2 mediated killing if applied in solution. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TNFRSF10B

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Alternative Name: TNFRSF10B / Killer / DR5 (TNFRSF10B Products)

Background: Name/Gene ID: TNFRSF10B
Family: TNF Receptor

Synonyms: TNFRSF10B, Cytotoxic TRAIL receptor-2, CD262 antigen, DR5, Death receptor 5, KILLER, TRAIL-R2, TRICK2B, TRAILR2, TRICK2A, TRICKB, TRICK2, CD262, Fas-like protein, TRAIL receptor 2, ZTNFR9

Gene ID: 8795

Pathways: p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity