Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) antibody

Antigen: Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5)

Synonyms: CAT2, ECAC1, OTRPC3, CaT2, Ecac1, MGC129346, MGC129347, D630033B11, TRPV5, ECAC

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN263199

Additional Information

Alternative name: TRPV5

Gene ID: 56302

Immunogen: C-SHRGWEILRQNT

Format: Affinity-purified

Description: All names and symbols: TRPV5 , transient receptor potential cation channel, subfamily V, member 5 , CAT2, ECAC1, OTRPC3, calcium transporter 2, epithelial calcium channel 1, osm-9-like TRP channel 3. Official Symbol: TRPV5 . RefSeq number(s): NP_062815.2

Specificity: Human, Mouse,Rat

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 85kDa band observed in Human Pancreas lysates (calculated MW of 82.6kDa according to NP_062815.2). Recommended concentration: 1-3µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Signaling, Metabolism

Restrictions: For Research Use only

Images

ABIN263199 (1 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: van der Eerden, Hoenderop, de Vries et al.: "The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 48, pp. 17507-12, 2005 (PubMed).