CSTB antibody (N-Term)

Catalog No. ABIN263931

Product Details anti-CSTB Antibody

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Binding Specificity: AA 1-98, N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSTB antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detetcts CSTB.

Characteristics: Synonyms: Stefin-B, CPI-B, CSTB, CST6, STFB, Liver thiol proteinase inhibitor

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human CSTB (1-98aa) purified from E. coli

Clone: 2F1

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot: 1: 1000 approx. 1: 3,000, starting diluton 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CSTB

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Alternative Name: Cystatin-B (CSTB Products)

Synonyms: CST6 antibody, EPM1 antibody, EPM1A antibody, PME antibody, STFB antibody, ULD antibody, CSTB antibody, Cyb antibody, Epm1 antibody, Stfb antibody, MGC189005 antibody, pme antibody, cst6 antibody, epm1 antibody, stfb antibody, AA960480 antibody, ARABIDOPSIS THALIANA PHYTOCYSTATIN 6 antibody, ATCYS6 antibody, ATCYSB antibody, cystatin B antibody, LOC100008600 antibody, LOC100136235 antibody, CPI1 antibody, cystatin B antibody, cystatin B (stefin B) antibody, cystatin 14a, tandem duplicate 2 antibody, cystatin-B antibody, CSTB antibody, Cstb antibody, cstb antibody, cst14a.2 antibody, CYSB antibody, cpi1 antibody, LOC101123265 antibody

Background: CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to from a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes in cells. CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus.Synonyms: CPI-B, CST6, CSTB, Liver thiol proteinase inhibitor, STFB, Stefin-B

Gene ID: 1476

UniProt: P04080

Pathways: Response to Water Deprivation