CYP4F11 antibody (C-Term)

Catalog No. ABIN264503

The Mouse Monoclonal anti-CYP4F11 antibody is suitable to detect CYP4F11 in samples from Human. It has been validated for WB, IHC (fro) and EIA.

Quick Overview for CYP4F11 antibody (C-Term) (ABIN264503)

Target: CYP4F11 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 11 (CYP4F11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYP4F11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: F21 P6 F5

Product Details anti-CYP4F11 Antibody

Binding Specificity: C-Term

Specificity: This Antibody reacts to Cytochrome P450 4F11.

Characteristics: Synonyms: Cytochrome P450 4F11, CYPIVF11

Purification: Purified

Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the Cterminus of the human CYP450 4F11 protein andmouse myeloma Ag8563 cells.

Isotype: IgG1

Application Details

Application Notes: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CYP4F11

Target: CYP4F11 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 11 (CYP4F11))

Alternative Name: CYP4F11

Background: The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2 % identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.Synonyms: CYPIVF11, Cytochrome P450 4F11

Gene ID: 57834

UniProt: Q9HBI6

Pathways: Monocarboxylic Acid Catabolic Process