PP5 antibody

Catalog No. ABIN265046

Product Details anti-PP5 Antibody

Target: PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PP5 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to PPP5C.

Purification: Purified

Immunogen: Synthetic peptide derived from the human protein phosphatase 5 protein.

Isotype: IgG

Application Details

Application Notes: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for PP5

Target: PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))

Alternative Name: PPP5C (PPP5C Products)

Synonyms: PP5 antibody, PPP5 antibody, PPT antibody, AU020526 antibody, pp5 antibody, MGC89961 antibody, fc83f08 antibody, im:7146608 antibody, wu:fc83f08 antibody, zgc:110801 antibody, PPP5C antibody, protein phosphatase 5 catalytic subunit antibody, protein phosphatase 5, catalytic subunit antibody, protein phosphatase 5, catalytic subunit S homeolog antibody, serine/threonine-protein phosphatase 5 antibody, PPP5C antibody, Ppp5c antibody, ppp5c.S antibody, ppp5c antibody, LOC592155 antibody, LOC100513542 antibody, LOC100564151 antibody, LOC100186268 antibody, LOC100208775 antibody

Background: Protein phosphatase 5 (PP5) is a novel human protein serine/threonine phosphatase of molecular weight of 58 kDa. It is made up of a C-terminal phosphatase catalytic domain and an N-terminal domain, which has four repeats of 34 amino acids, three of which are tandemly arranged. The phosphatase domain contains all of the invariant motifs of the PP1/PP2A/PP2B gene family. However, it is not closely related to any other known member of this family of phosphatases. Thus it makes up a new subfamily of phosphatases. PP5 expressed in bacteria has been shown to dephosphorylate serine residues in proteins and is more sensitive than PP1 to the tumor promoter okadaic acid. PP5 appears to be localized to the nucleus suggesting that, like other nuclear tetratricopeptide (TPR)-containing proteins, it may playa role in the regulation of RNA biogenesis and mitosis.Synonyms: PP-t, PP5, PPP5, PPT, Protein phosphatase T, Serine/threonine-protein phosphatase 5

Gene ID: 5536

NCBI Accession: NP_006238

UniProt: P53041