BAG5 antibody

Catalog No. ABIN265064

Product Details anti-BAG5 Antibody

Target: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAG5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody reacts to BAG5.

Purification: Purified

Immunogen: Synthetic peptide derived from the human BAG-5 protein.

Application Details

Application Notes: Western blot: 5 - 10 μg/mL. Immunohistochemistry on paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for BAG5

Target: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Alternative Name: BAG5 (BAG5 Products)

Synonyms: BAG-5 antibody, bag-5 antibody, 1600025G07Rik antibody, 4930405J06Rik antibody, zgc:114117 antibody, BAG5 antibody, ATBAG5 antibody, BCL-2-associated athanogene 5 antibody, F12F1.7 antibody, F12F1_7 antibody, BCL2 associated athanogene 5 antibody, BCL2-associated athanogene 5 antibody, BCL-2-associated athanogene 5 antibody, BAG5 antibody, bag5 antibody, Bag5 antibody

Background: It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.Synonyms: BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, KIAA0873

Gene ID: 9606

UniProt: Q9UL15

Pathways: SARS-CoV-2 Protein Interactome