BCL2-Associated Athanogene 5 (BAG5) antibody

Details for Product No. ABIN265064
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Antigen
Synonyms BAG-5, 1600025G07Rik, 4930405J06Rik, BAG5, zgc:114117, bag-5
Reactivity
Rat (Rattus)
(58), (20), (19), (13), (12), (2)
Host
Rabbit
(40), (13), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(42), (22), (12), (10), (4), (4), (3), (2), (1), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN265064
Quantity 0.1 mg
Price
324.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide derived from the human BAG-5 protein.
Specificity This antibody reacts to BAG5.
Purification Purified
Alternative Name BAG5
Background It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.
Alternate names: BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, KIAA0873
NCBI Accession 9606
UniProt Q9UL15
Application Notes Western blot: 5 - 10 ug/ml. Immunohistochemistry on paraffin Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer Phosphate buffered saline with 0.08% sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only.
Expiry Date 12 months
Background publications Takayama, Xie, Reed: "An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 781-6, 1999 (PubMed).

Hosts (40), (13), (8)
Reactivities (58), (20), (19), (13), (12), (2)
Applications (42), (22), (12), (10), (4), (4), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (7), (6), (3), (2), (1), (1), (1)
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