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BCL2-Associated Athanogene 5 (BAG5) antibody

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Antigen
  • BAG5
  • zgc:114117
  • bag-5
  • BAG-5
  • 1600025G07Rik
  • 4930405J06Rik
Reactivity
Rat (Rattus)
140
32
32
5
5
3
Host
Rabbit
87
45
10
Clonality
Polyclonal
Conjugate
Un-conjugated
9
9
9
5
5
5
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
106
70
14
11
9
8
5
2
2
1
1
Supplier
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Immunogen Synthetic peptide derived from the human BAG-5 protein.
Specificity This antibody reacts to BAG5.
Purification Purified
Alternative Name BAG5 (BAG5 Antibody Abstract)
Background It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.Synonyms: BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, KIAA0873
Gene ID 9606
UniProt Q9UL15
Pathways
Application Notes Western blot: 5 - 10 μg/mL. Immunohistochemistry on paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer Phosphate buffered saline with 0.08 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
Background publications Takayama, Xie, Reed: "An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 781-6, 1999 (PubMed).