Forkhead Box P3 (FOXP3) antibody

Details for Product No. ABIN265254
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Antigen
Synonyms foxp3, FOXP3, AIID, DIETER, IPEX, PIDX, XPID, JM2, scurfin, sf, RGD1562112
Reactivity
Human
(199), (138), (61), (15), (15), (14), (12), (7)
Host
Rabbit
(160), (61), (44), (14)
Clonality
Polyclonal
Conjugate
Un-conjugated
(17), (16), (15), (9), (7), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application
Western Blotting (WB)
(177), (87), (80), (53), (41), (20), (11), (10), (10), (8), (7), (7), (3), (2)
Pubmed 3 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN265254
368.50 $
Plus shipping costs $45.00

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  • +1 404 474 4654
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Immunogen Synthetic peptide derived from human FOXP3 protein
Specificity This antibody detects FOXP3.
Purification Purified
Alternative Name FOXP3
Background Probable transcription factor. Plays a critical role in the control of immune response. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X- linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.
Alternate names: Forkhead box protein P3, IPEX, JM2, Scurfin
Gene ID 50943
NCBI Accession NP_001107849
UniProt Q9BZS1
Research Area Immunology, Adaptive Immunity, Transcription Factors
Application Notes Western blot (1-5 g). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer Phosphate buffered saline with 0.08% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
Expiry Date 12 months
Background publications Wildin, Ramsdell, Peake et al.: "X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy." in: Nature genetics, Vol. 27, Issue 1, pp. 18-20, 2001 (PubMed).

Bennett, Christie, Ramsdell et al.: "The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3." in: Nature genetics, Vol. 27, Issue 1, pp. 20-1, 2001 (PubMed).

Brunkow, Jeffery, Hjerrild et al.: "Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse." in: Nature genetics, Vol. 27, Issue 1, pp. 68-73, 2001 (PubMed).

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