EFNA4 antibody

Catalog No. ABIN265402

This Rabbit Polyclonal antibody specifically detects EFNA4 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for EFNA4 antibody (ABIN265402)

Target: EFNA4 (Ephrin A4 (EFNA4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFNA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EFNA4 Antibody

Specificity: This antibody detects endogenous levels of Ephrin-A4 protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: ELISA: 1: 5000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EFNA4

Target: EFNA4 (Ephrin A4 (EFNA4))

Alternative Name: Ephrin-A4

Background: Ephrin A4 is also known as LERK4 or ELF4. Ephrin A4 binds EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, and EphB1. To date, at least 14 members of the Eph receptor family and a family of 8 ligands have been identified. Ligands of Eph family receptors are structurally related membrane bound proteins that can be subdivided into two major subclasses: ephrin A and ephrin B. Ligands in the ephrin A subclass, including the prototype family member ephrin A1 (B61), are membrane associated through glycosylphosphatidyl inositollinkages, whereas ephrin B subclass consists of ligands with transmembrane domains. The general role of the Eph family is in mediating repulsive cell to cell interaction, as suggested by studies of axonal guidance and neural crest cell migration.Synonyms: EFNA4, EPH-related receptor tyrosine kinase ligand 4, EPLG4, Epl4, LERK-4, LERK4

Molecular Weight: approx. 95 kDa

Gene ID: 1945

NCBI Accession: NP_005218

UniProt: P52798

Pathways: RTK Signaling