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CXCR2 antibody (APC)

CXCR2 Reactivity: Human FACS, ICFC Host: Mouse Monoclonal 5E8-CXCR2 APC
Catalog No. ABIN2658505
  • Target See all CXCR2 Antibodies
    CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
    Reactivity
    • 79
    • 39
    • 24
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 72
    • 10
    • 1
    • 1
    Mouse
    Clonality
    • 74
    • 9
    • 1
    Monoclonal
    Conjugate
    • 47
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CXCR2 antibody is conjugated to APC
    Application
    • 51
    • 31
    • 22
    • 18
    • 16
    • 14
    • 13
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    Clone
    5E8-CXCR2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CXCR2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
    Alternative Name
    CD182 (CXCR2 Products)
    Synonyms
    CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody
    Background
    CXCR2 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor B (IL-8RB), CD182, and CD128b. It is a CXC chemokine receptor belongs to G protein-coupled receptor (GPCR) family. CXCR2 is expressed as homodimer or heterodimer with CXCR1 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. CXCR2 mediates neutrophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO-α,β,γ (CXCL1, CXCL2, CXCL3).
    Pathways
    cAMP Metabolic Process
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