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TNFRSF10B antibody (Biotin)

TNFRSF10B Reactivity: Mouse WB, IHC, ICFC, ELISA (Capture) Host: Hamster Monoclonal MD5-1 Biotin

Catalog No. ABIN2661014

Datasheet as PDF

Target See all TNFRSF10B Antibodies

TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Reactivity
100

18

4

1

1
Mouse
Host
71

36

1

1

1

1
Hamster
Clonality
66

42

2
Monoclonal
Conjugate
68

10

6

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This TNFRSF10B antibody is conjugated to Biotin
Application
73

32

30

23

15

14

14

13

12

9

8

5

4

3

3

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Intracellular Flow Cytometry (ICFC), ELISA (Capture)

Purification

The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Clone

MD5-1

Isotype

IgG

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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 234-435) antibody
TNFRSF10B Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) antibody
TNFRSF10B Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 233-440) antibody
TNFRSF10B Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (N-Term) antibody
TNFRSF10B Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-210) antibody
TNFRSF10B Reactivity: Human ELISA Host: Mouse Monoclonal 2H5B8 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 266-393) antibody
TNFRSF10B Reactivity: Human IHC, StM Host: Mouse Monoclonal DR5-3381 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 1-440) antibody
TNFRSF10B Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 71-170) antibody
TNFRSF10B Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 2D6 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 301-381) antibody
TNFRSF10B Reactivity: Human WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (Extracellular Domain) antibody (APC)
TNFRSF10B Reactivity: Human FACS Host: Mouse Monoclonal DR5-01-1 APC

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

0.5 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Do not freeze.

Storage

4 °C

Storage Comment

The antibody solution should be stored undiluted between 2°C and 8°C.
Target

TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Alternative Name

CD262 (TNFRSF10B Products)

Background

CD262 is a 55 kD protein also known as DR5, TRAIL-R2, Apo-2, TRICK2, and KILLER. DR5 is member 10B of the TNF receptor superfamily (TNFRSF10B), widely expressed in normal tissues and some tumor cell lines. The DR5 receptor binds to TRAIL and interacts with the cytoplasmic proteins TRADD and RIP. TRAIL binding to DR5 activates NF- κB and induces apoptosis. DR5 is induced by wild-type p53.

Pathways

p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity