CD200 Receptor 3 (CD200R3) antibody (PE)

Details for Product No. ABIN2662519, Supplier: Log in to see
Antigen
  • 4733401I18Rik
  • 4833409J19Rik
  • AI505817
  • BB106877
  • mCD200RLb
  • CD200 receptor 3
  • Cd200r3
Reactivity
Mouse (Murine)
17
Host
Rat
11
4
2
Clonality (Clone)
Monoclonal ()
Conjugate
PE
6
4
1
Application
Flow Cytometry (FACS)
14
3
2
2
2
1
Options
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Clone Ba13
Isotype IgG2a kappa
Purification The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Alternative Name CD200R3 (CD200R3 Antibody Abstract)
Background CD200R3, also known as CD200RLb and OX-2 Receptor 3, is a disulfide-linked dimeric CD200R-like receptor which belongs to immunoglobulin superfamily. Its positively charged amino acid lysine associates with ITAM- or YxxM motif-bearing adaptor molecules such as DAP12, DAP10, FcRγ, and CD3ζ. CD200R3 functions as an activating receptor to regulate IgE independent immune response.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.
Supplier Images
Flow Cytometry (FACS) image for anti-CD200 Receptor 3 (CD200R3) antibody (PE) (ABIN2662519) anti-CD200 Receptor 3 (CD200R3) antibody (PE)
Flow Cytometry (FACS) image for anti-CD200 Receptor 3 (CD200R3) antibody (PE) (ABIN2662519) anti-CD200 Receptor 3 (CD200R3) antibody (PE) (Image 2)
Background publications Schwartz, Oeser, Prazeres da Costa, Layland, Voehringer: "T cell-derived IL-4/IL-13 protects mice against fatal Schistosoma mansoni infection independently of basophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 7, pp. 3590-9, 2014 (PubMed).

Schwartz, Turqueti-Neves, Hartmann, Yu, Nimmerjahn, Voehringer: "Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 48, pp. E5169-77, 2014 (PubMed).

Sato, Eizumi, Fukaya, Fujita, Sato, Takagi, Yamamoto, Yamashita, Hijikata, Kitamura, Ohara, Yamasaki, Saito, Sato: "Naturally occurring regulatory dendritic cells regulate murine cutaneous chronic graft-versus-host disease." in: Blood, Vol. 113, Issue 19, pp. 4780-9, 2009 (PubMed).

Kojima, Obata, Mukai, Sato, Takai, Minegishi, Karasuyama: "Mast cells and basophils are selectively activated in vitro and in vivo through CD200R3 in an IgE-independent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 10, pp. 7093-100, 2007 (PubMed).

Voehringer, Rosen, Lanier, Locksley: "CD200 receptor family members represent novel DAP12-associated activating receptors on basophils and mast cells." in: The Journal of biological chemistry, Vol. 279, Issue 52, pp. 54117-23, 2004 (PubMed).