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FASL antibody
FASL
Reactivity: Human
FACS
Host: Mouse
Monoclonal
NOK-1
unconjugated
Product Details anti-FASL Antibody
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Target
See all FASL Antibodies
FASL
(Fas Ligand (TNF Superfamily, Member 6) (FASL))
Reactivity
All reactivities for FASL antibodies
Human
Host
All hosts for FASL antibodies
Mouse
Clonality
All clonalities for FASL antibodies
Monoclonal
Conjugate
All conjugates for FASL antibodies
This FASL antibody is un-conjugated
Application
All applications for FASL antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
NOK-1
Isotype
IgG1 kappa
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Discover our top product FASL Primary Antibody
Alternatives
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anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 196-281) antibody
FASL
Reactivity: Human, Mouse, Rat, Pig
WB, FACS, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for FASL
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Target
FASL
(Fas Ligand (TNF Superfamily, Member 6) (FASL))
Alternative Name
CD178 (FASL Products )
Synonyms
ALPS1B antibody, APT1LG1 antibody, APTL antibody, CD178 antibody, CD95-L antibody, CD95L antibody, FASL antibody, TNFSF6 antibody, fasl antibody, Fas-L antibody, Faslg antibody, Tnfsf6 antibody, gld antibody, Apt1Lg1 antibody, Fasl antibody, FASLG antibody, zgc:162027 antibody, Fas ligand antibody, Fas ligand L homeolog antibody, Fas ligand (TNF superfamily, member 6) antibody, FASLG antibody, faslg.L antibody, Fasl antibody, Faslg antibody, faslg antibody
Background
CD178 is a 38-42 kD type II glycoprotein also known as Fas ligand and CD95L. CD178 belongs to the TNF superfamily and is expressed on activated T lymphocytes, NK cells, monocytes, and granulocytes. CD178 is also expressed on parenchymal cells of the retina and cornea, retinal pigment epithelial cells, and testis. The extracellular region of FasL can be cleaved by matrix metalloproteinases (MMPs) to give rise to a 26 kD soluble protein. CD178 binds to CD95, a member of the TNFR superfamily, to induce apoptosis. CD95/CD95L interactions play an important role in the maintenance of peripheral tolerance and survival.
Pathways
Apoptosis , EGFR Signaling Pathway , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity
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