CRTAM antibody

Catalog No. ABIN2664609

Product Details anti-CRTAM Antibody

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CRTAM antibody is un-conjugated

Application: ELISpot (Detection) (ELISPOT (Detection)), ELISA (Detection)

Purification: The antibody was purified by affinity chromatography.

Clone: 11-5-CRTAM

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CRTAM

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Alternative Name: CD355 (CRTAM Products)

Synonyms: TAD antibody, cTADS antibody, MGC82176 antibody, CRTAM antibody, CD355 antibody, cytotoxic and regulatory T-cell molecule antibody, cytotoxic and regulatory T-cell molecule L homeolog antibody, cytotoxic and regulatory T cell molecule antibody, CRTAM antibody, crtam.L antibody, Crtam antibody

Background: Class-I MHC-restricted T-cell associated molecule (CRTAM), designated as CD355, is an Ig domain like type I transmembrane receptor, which belongs to the nectin family. In the immune system, CRTAM is strictly expressed on activated NK cells and activated CD8-positive T cells. By binding its ligand Nectin-like molecule 2 (Necl2), CRTAM plays an important role in mediating cell adhesion and migration.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation