Asialo-GM1 antibody
Reactivity: All Species
FACS, IF, ICC, IP, IHC, WB
Host: Rabbit
Polyclonal
Poly21460
unconjugated
1 image
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- Target
- Asialo-GM1
- Reactivity
- All Species
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
- Brand
- Ultra-LEAF™
- Endotoxin Level
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- Clone
- Poly21460
- Isotype
- IgG
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid, Lyophilized
- Preservative
- Azide free
- Handling Advice
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- Asialo-GM1
- Background
- GM1 is a ganglioside, a type of glycosphingolipid with a single sialic acid group. Asialo-GM1 is a GM1 derivative without a sialic acid group. It is expressed on NK cells, basophils, monocytes/macrophages, and T cells. It is particularly expressed on very early thymocytes, but the expression decreases as the cells mature and become Thy-1 + . The highest expression is detected on neuronal tissues. This molecule has been shown to be involved in microbial pathogenesis. Antibodies specific for Asialo-GM1 are elevated in dementia, lupus, and Guillain-Barré syndrome.
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