CD166 antibody

Catalog No. ABIN2689015

Product Details anti-CD166 Antibody

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD166 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Brand: BD Pharmingen™

Characteristics: Reacts with the activated leukocyte cell adhesion molecule (ALCAM), a 100-105 kDa transmembrane glycoprotein, also known as the CD6 ligand, CD166. It is composed of an immunoglobulin-like extracellular domain, a transmembrane region and a short cytoplasmic tail. ALCAM belongs to the Ig superfamily of proteins and is expressed on neurons, activated T cells, activated monocytes, epithelial cells and fibroblasts. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T-cell development. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood monocytes analyzed by flow cytometry.

BD Pharmingen™ Purified Mouse Anti-Human CD166 - Purified - Clone 3A6 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: 3A6

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD166 antibody (ABIN2689015)

Aruffo, Bowen, Patel, Haynes, Starling, Gebe, Bajorath: "CD6-ligand interactions: a paradigm for SRCR domain function?" in: Immunology today, Vol. 18, Issue 10, pp. 498-504, (1998) (PubMed).

Patel, Wee, Whichard, Bowen, Pesando, Aruffo, Haynes: "Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells." in: The Journal of experimental medicine, Vol. 181, Issue 4, pp. 1563-8, (1995) (PubMed).

Target Details for CD166

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Alternative Name: CD166 (ALCAM Products)

Synonyms: CD166 antibody, MEMD antibody, ALCAM antibody, BEN antibody, DM-GRASP antibody, JC7 antibody, SC1 antibody, AI853494 antibody, MuSC antibody, alcam antibody, cd166 antibody, memd antibody, fb53h09 antibody, fb80a10 antibody, nlcam antibody, si:ch211-190h2.4 antibody, wu:fb53h09 antibody, wu:fb80a10 antibody, wu:fc14b01 antibody, activated leukocyte cell adhesion molecule antibody, activated leukocyte cell adhesion molecule a antibody, activated leukocyte cell adhesion molecule L homeolog antibody, CD166 antigen homolog antibody, activated leukocyte cell adhesion molecule b antibody, ALCAM antibody, Alcam antibody, alcama antibody, alcam.L antibody, alcam antibody, cd166 antibody, alcamb antibody