Homeobox C6 antibody

Catalog No. ABIN272159

Product Details anti-Homeobox C6 Antibody

Target: Homeobox C6 (HOXC6)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Homeobox C6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of Hox-C6 protein. (region surrounding Gly220)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE!

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for Homeobox C6

Target: Homeobox C6 (HOXC6)

Alternative Name: HOXC6 / HOX3C (HOXC6 Products)

Synonyms: CP25 antibody, HHO.C8 antibody, HOX3 antibody, HOX3C antibody, Hox-3.3 antibody, Hox-6.1 antibody, HOX-C6 antibody, ZF-61 antibody, hoxc-6 antibody, hoxc6 antibody, zgc:101882 antibody, HOXC6 antibody, Hoxc-6 antibody, xlhbox1 antibody, FrHOXC-6 antibody, HoxC6a antibody, hoxy6 antibody, HOXC-6 antibody, homeobox C6 antibody, homeobox C6a antibody, homeo box C6 antibody, homeobox A6 antibody, homeobox C6 S homeolog antibody, homeobox C6b antibody, HOXC6 antibody, Hoxc6 antibody, hoxc6a antibody, HOXA6 antibody, hoxc6.S antibody, hoxc6 antibody, hoxc6b antibody

Background: The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian Hox gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. Hox genes that occupy the same relative position along the 5' to 3' coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent Hox genes on the same chromosome. HoxC6 sequence-specific transcription factor is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. HoxC6 may be a novel potential therapeutic target for prostate cancer.Synonyms: CP25, HHO.C8, Homeobox protein Hox-C6, Hox-3C

Molecular Weight: approx. 26 kDa

Gene ID: 3223

NCBI Accession: NP_004494

UniProt: P09630