TAS1R1 antibody (Middle Region)

Catalog No. ABIN2774434

Product Details anti-TAS1R1 Antibody

Target: TAS1R1 (Taste Receptor, Type 1, Member 1 (TAS1R1))

Binding Specificity: Middle Region

Reactivity: Human, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAS1R1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QKRAVPGLKA FEEAYARADK KAPRPCHKGS WCSSNQLCRE CQAFMAHTMP

Predicted Reactivity: Guinea Pig: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against TAS1R1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human TAS1R1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 841 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAS1R1

Target: TAS1R1 (Taste Receptor, Type 1, Member 1 (TAS1R1))

Alternative Name: TAS1R1 (TAS1R1 Products)

Synonyms: GPR70 antibody, T1R1 antibody, TR1 antibody, Gpr70 antibody, T1r1 antibody, taste receptor, type 1, member 1 antibody, taste 1 receptor member 1 antibody, tas1r1 antibody, TAS1R1 antibody, Tas1r1 antibody

Background: The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: GPR70, T1R1, TR1, gm148
Protein Interaction Partner: TAS1R3,
Protein Size: 841

Molecular Weight: 90 kDa

Gene ID: 80835

NCBI Accession: NM_138697, NP_619642

UniProt: Q7RTX1