DSN1 antibody (C-Term)

Catalog No. ABIN2774435

Product Details anti-DSN1 Antibody

Target: DSN1 (Kinetochore-associated protein DSN1 homolog (DSN1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Horse, Dog, Guinea Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DSN1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MTYLGSSQNE VLNTKPDYQK ILQNQSKVFD CMELVMDELQ GSVKQLQAFM

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DSN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DSN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 249 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DSN1

Target: DSN1 (Kinetochore-associated protein DSN1 homolog (DSN1))

Alternative Name: DSN1 (DSN1 Products)

Synonyms: 1700022L09Rik antibody, AW552447 antibody, C20orf172 antibody, KNL3 antibody, MIS13 antibody, dJ469A13.2 antibody, hKNL-3 antibody, DSN1 homolog, MIS12 kinetochore complex component antibody, Dsn1 antibody, DSN1 antibody

Background: This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants.
Alias Symbols: C20orf172, FLJ13346, KNL3, MGC32987, MIS13, dJ469A13.2, hKNL-3
Protein Interaction Partner: ZWINT, SUGT1, CBX5, APP, MIS12, NSL1, PMF1, HSP90AA1, SKA2, UBC, SUMO2, PIK3R3, AIMP2, Casc5, Ndc80, Dsn1, Bub1b, Bub1, CBX3,
Protein Size: 249

Molecular Weight: 28 kDa

Gene ID: 79980

NCBI Accession: NM_001145317, NP_001138789

UniProt: Q5JW55