TAF7 antibody (N-Term)

Catalog No. ABIN2774669

Product Details anti-TAF7 Antibody

Target: TAF7 (TAF7 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 55kDa (TAF7))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MSKSKDDAPH ELESQFILRL PPEYASTVRR AVQSGHVNLK DRLTIELHPD

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against TAF7. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TAF7

Application Details

Application Notes: WB Suggested Anti-TAF7 Antibody Titration: 5.0-8.0 µg/mL
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 349 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAF7

Target: TAF7 (TAF7 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 55kDa (TAF7))

Alternative Name: TAF7 (TAF7 Products)

Background: The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II.
Alias Symbols: TAF2F, TAFII55
Protein Interaction Partner: UBC, FAU, RBM6, MED26, HIST3H3, LEO1, TAF9B, TRRAP, TAF10, TAF9, TAF6, TAF5, TAF4, TAF1, TBP, ERCC1, MAP1LC3B, CPSF1, CDK9, CDK7, CCNT1, TAF3, TAF8, SETD7, VDR, THRA, ZSCAN1, TRIM22, IKBKG, GATA1, TAF12, TAF11, TAF15, TAF7, TAF2, TRIM24, AHR, HSF1, ERCC3,
Protein Size: 349

Molecular Weight: 40 kDa

Gene ID: 6879

NCBI Accession: NM_005642, NP_005633

UniProt: Q15545

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway