GTSE1 antibody (N-Term)

Catalog No. ABIN2775433

Product Details anti-GTSE1 Antibody

Target: GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTSE1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NNPVPEQPPL PTSESPFAWS PLAGEKFVEV YKEAHLLALH IESSSRNQAA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GTSE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTSE1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 720 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTSE1

Target: GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))

Alternative Name: GTSE1 (GTSE1 Products)

Synonyms: gtse1 antibody, MGC81588 antibody, MGC89498 antibody, GTSE1 antibody, fb70b04 antibody, fj88g09 antibody, wu:fb70b04 antibody, wu:fj88g09 antibody, wu:fy65d12 antibody, MGC114722 antibody, B99 antibody, Gtse-1 antibody, RGD1563164 antibody, G2 and S-phase expressed 1 S homeolog antibody, G2 and S-phase expressed 1 antibody, G-2 and S-phase expressed 1 antibody, G2 and S-phase expressed 1 L homeolog antibody, G two S phase expressed protein 1 antibody, gtse1.S antibody, gtse1 antibody, GTSE1 antibody, gtse1.L antibody, Gtse1 antibody

Background: GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
Alias Symbols: B99
Protein Interaction Partner: UBC, HNRNPD, BARD1, SH3KBP1, SUMO2, USP11,
Protein Size: 720

Molecular Weight: 76 kDa

Gene ID: 51512

NCBI Accession: NM_016426, NP_057510

UniProt: Q9NYZ3