NKD1 antibody (N-Term)

Catalog No. ABIN2776729

Product Details anti-NKD1 Antibody

Target: NKD1 (Naked Cuticle Homolog 1 (NKD1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: ELVGDVLRDT LSEEEEDDFR LEVALPPEKT DGLGSGDEKK MERVSEPCPG

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 85%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against NKD1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NKD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 470 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NKD1

Target: NKD1 (Naked Cuticle Homolog 1 (NKD1))

Alternative Name: NKD1 (NKD1 Products)

Synonyms: 2810434J10Rik antibody, 9030215G15Rik antibody, Nkd antibody, Naked1 antibody, naked cuticle homolog 1 antibody, naked cuticle 1 homolog (Drosophila) antibody, naked cuticle homolog 1 (Drosophila) antibody, NKD1 antibody, Nkd1 antibody, nkd1 antibody

Background: In the mouse, Nkd is a Dishevelled -binding protein that functions as a negative regulator of the Wnt-beta-catenin -Tcf signaling pathway.In the mouse, Nkd is a Dishevelled (see DVL1, MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1, MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM].
Alias Symbols: Naked1
Protein Interaction Partner: DVL3,
Protein Size: 470

Molecular Weight: 52 kDa

Gene ID: 85407

NCBI Accession: NM_033119, NP_149110

UniProt: Q969G9