MYH7 antibody (Middle Region)

Catalog No. ABIN2776777

Product Details anti-MYH7 Antibody

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYH7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TLEDQMNEHR SKAEETQRSV NDLTSQRAKL QTENGELSRQ LDEKEALISQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Myh7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1935 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MYH7 antibody (ABIN2776777)

Rouillon, Poupiot, Zocevic, Amor, Léger, Garcia, Camadro, Wong, Pinilla, Cosette, Coenen-Stass, Mcclorey, Roberts, Wood, Servais, Udd, Voit, Richard, Svinartchouk: "Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies." in: Human molecular genetics, Vol. 24, Issue 17, pp. 4916-32, (2016) (PubMed).

Tijore, Cai, Nai, Zhuyun, Yu, Tay, Lim, Chen, Tan: "Role of Cytoskeletal Tension in the Induction of Cardiomyogenic Differentiation in Micropatterned Human Mesenchymal Stem Cell." in: Advanced healthcare materials, Vol. 4, Issue 9, pp. 1399-407, (2015) (PubMed).

Tijore, Hariharan, Yu, Lam, Wen, Tay, Ahmed, Tan: "Investigating the spatial distribution of integrin β₁ in patterned human mesenchymal stem cells using super-resolution imaging." in: ACS applied materials & interfaces, Vol. 6, Issue 18, pp. 15686-96, (2014) (PubMed).

Target Details for MYH7

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Alternative Name: Myh7 (MYH7 Products)

Synonyms: CMD1S antibody, CMH1 antibody, MPD1 antibody, MYHCB antibody, SPMD antibody, SPMM antibody, Myhcb antibody, AMHC1 antibody, myosin antibody, myosin-7 antibody, B-MHC antibody, MyHC-I antibody, Myhc-b antibody, beta-MHC antibody, myosin heavy chain 7 antibody, myosin, heavy chain 7, cardiac muscle, beta antibody, myosin, heavy polypeptide 7, cardiac muscle, beta antibody, MYH7 antibody, Myh7 antibody

Background: Myh7 play a role in muscle contraction.
Alias Symbols: Myhc-b, Myhcb, B-MHC, MyHC-I, beta-MHC
Protein Size: 1935

Molecular Weight: 223 kDa

Gene ID: 140781

NCBI Accession: NM_080728, NP_542766

UniProt: Q91Z83