HMGCS2 antibody (C-Term)

Catalog No. ABIN2776881

Product Details anti-HMGCS2 Antibody

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Goat, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGCS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DLPKRLASRK CVSPEEFTEI MNQREQFYHK VNFSPPGDTN SLFPGTWYLE

Predicted Reactivity: Cow: 79%, Dog: 100%, Goat: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HMGCS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HMGCS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 508 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMGCS2

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Alternative Name: HMGCS2 (HMGCS2 Products)

Synonyms: 1300002P16 antibody, mHS antibody, DDBDRAFT_0219349 antibody, DDBDRAFT_0219924 antibody, DDB_0219349 antibody, DDB_0219924 antibody, Hmgcs1 antibody, Mt3h3mg antibody, hmgCoA antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 2 antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 antibody, hydroxymethylglutaryl-CoA synthase antibody, hydroxymethylglutaryl-coa synthase antibody, 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 antibody, HMGCS2 antibody, Hmgcs2 antibody, mvaS antibody, CNC05080 antibody, HMCS1 antibody, hgsA antibody, MFER_RS00425 antibody, LOC100285783 antibody, ECU10_0510 antibody, Eint_100450 antibody

Background: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Alias Symbols: -
Protein Interaction Partner: UBC, APP, YWHAQ,
Protein Size: 508

Molecular Weight: 56 kDa

Gene ID: 3158

NCBI Accession: NM_005518, NP_005509

UniProt: P54868

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha