CSHL1 antibody (C-Term)

Catalog No. ABIN2777075

Product Details anti-CSHL1 Antibody

Target: CSHL1 (Chorionic Somatomammotropin Hormone-Like 1 (CSHL1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Goat, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSHL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GQTLKQTYSK FDTNSHNHDA LLKNYGLLHC FRKDMDKVET FLRMVQCRSV

Predicted Reactivity: Cow: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against CSHL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CSHL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 199 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CSHL1

Target: CSHL1 (Chorionic Somatomammotropin Hormone-Like 1 (CSHL1))

Alternative Name: CSHL1 (CSHL1 Products)

Synonyms: CSHL1 antibody, PL-D antibody, CS-5 antibody, CSHP1 antibody, CSL antibody, hCS-L antibody, placental lactogen PL-D antibody, chorionic somatomammotropin hormone like 1 antibody, PL-D antibody, CSHL1 antibody

Background: CSHL1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: CS-5, CSHP1, CSL, MGC149868, hCS-L
Protein Interaction Partner: MAML2, MAML3,
Protein Size: 199

Molecular Weight: 20 kDa

Gene ID: 1444

NCBI Accession: NM_022581, NP_072103

UniProt: Q14406