JDP2 antibody (N-Term)

Catalog No. ABIN2777349

Product Details anti-JDP2 Antibody

Target: JDP2 (Jun Dimerization Protein 2 (JDP2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JDP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LPGLGPLTGL PSSALTVEEL KYADIRNLGA MIAPLHFLEV KLGKRPQPVK

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against JDP2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 163 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for JDP2

Target: JDP2 (Jun Dimerization Protein 2 (JDP2))

Alternative Name: JDP2 (JDP2 Products)

Synonyms: JUNDM2 antibody, JDP2 antibody, Jundm2 antibody, Jundp2 antibody, TIF antibody, fk87c02 antibody, wu:fk87c02 antibody, zgc:92851 antibody, Jun dimerization protein 2 antibody, Jun dimerization protein 2b antibody, JDP2 antibody, Jdp2 antibody, jdp2b antibody

Background: JDP2 is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. It is involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. It can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. It may control transcription via direct regulation of the modification of histones and the assembly of chromatin.
Alias Symbols: JUNDM2
Protein Interaction Partner: HDAC10, HDAC5, HDAC6, HDAC4, HDAC1, ELAVL1, PGR, JDP2, ATF2, GTF2H1, KAT2B, SNW1, MAPK9, EP300, MAPK8, MAPK14, CREBBP, JUND, JUNB, JUN, IRF2BP1, ATF7, UBC,
Protein Size: 163

Molecular Weight: 19 kDa

Gene ID: 122953

NCBI Accession: NM_130469, NP_569736

UniProt: Q8WYK2

Pathways: Chromatin Binding