BCL11A antibody (C-Term)

Catalog No. ABIN2777718

Product Details anti-BCL11A Antibody

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL11A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GTGSGGSTPH ISGPGPGRPS SKEGRRSDTC SSHTPIRRST QRAQDVWQFS

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against BCL11A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human BCL11B

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BCL11A

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Alternative Name: BCL11A (BCL11A Products)

Synonyms: 2810047E18Rik antibody, BCL-11A antibody, Ctip1 antibody, D930021L15Rik antibody, Evi9 antibody, Evi9a antibody, Evi9b antibody, Evi9c antibody, mKIAA1809 antibody, BCL11A-L antibody, BCL11A-S antibody, BCL11A-XL antibody, BCL11a-M antibody, CTIP1 antibody, EVI9 antibody, HBFQTL5 antibody, ZNF856 antibody, bcl11a antibody, wu:fi09f10 antibody, zgc:136898 antibody, B cell CLL/lymphoma 11A (zinc finger protein) antibody, B-cell CLL/lymphoma 11A antibody, B-cell CLL/lymphoma 11A L homeolog antibody, B-cell CLL/lymphoma 11Aa antibody, Bcl11a antibody, BCL11A antibody, bcl11a.L antibody, bcl11aa antibody

Background: This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: ATL1, RIT1, CTIP2, CTIP-2, ZNF856B, ATL1-beta, ATL1-alpha, ATL1-delta, ATL1-gamma, hRIT1-alpha
Protein Size: 442

Molecular Weight: 48 kDa

Gene ID: 64919

NCBI Accession: NM_001282237, NP_001269166

UniProt: Q9C0K0

Pathways: Regulation of Cell Size