EPB42 antibody (Middle Region)

Catalog No. ABIN2778127

Product Details anti-EPB42 Antibody

Target: EPB42 (erythrocyte Membrane Protein Band 4.2 (EPB42))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Guinea Pig, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPB42 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ISTKGVGSDR CEDITQNYKY PEGSLQEKEV LERVEKEKME REKDNGIRPP

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against EPB42. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EPB42

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 721 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EPB42

Target: EPB42 (erythrocyte Membrane Protein Band 4.2 (EPB42))

Alternative Name: EPB42 (EPB42 Products)

Synonyms: PA antibody, SPH5 antibody, Epb4.2 antibody, Epb42 antibody, erythrocyte membrane protein band 4.2 antibody, EPB42 antibody, Epb42 antibody

Background: Erythrocyte membrane protein band 4.2 is an ATP-binding protein which may regulate the association of protein 3 with ankyrin. It probably has a role in erythrocyte shape and mechanical property regulation. Mutations in the EPB42 gene are associated with recessive spherocytic elliptocytosis and recessively transmitted hereditary hemolytic anemia.
Alias Symbols: PA, SPH5
Protein Interaction Partner: MAPK14, SPINK7, BLOC1S4, STX12, CD47, SLC4A2, KRAS, ANK1, SPTAN1, EPB41, DMTN, SLC4A1, ANK2,
Protein Size: 721

Molecular Weight: 80 kDa

Gene ID: 2038

NCBI Accession: NM_000119, NP_000110

Pathways: Transition Metal Ion Homeostasis