ATP5G2 antibody (N-Term)

Catalog No. ABIN2778685

Product Details anti-ATP5G2 Antibody

Target: ATP5G2 (ATP Synthase, H+ Transporting, Mitochondrial Fo Complex, Subunit C2 (Subunit 9) (ATP5G2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Pig, Sheep, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP5G2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SRPLSAVVLK RPEILTDESL SSLAVSCPLT SLVSSRSFQT SAISRDIDTA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against ATP5G2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATP5G2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 157 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ATP5G2 antibody (ABIN2778685)

Nath: "Cell biology: pathogen propulsion." in: Nature, Vol. 427, Issue 6973, pp. 407, (2004) (PubMed).

Target Details for ATP5G2

Target: ATP5G2 (ATP Synthase, H+ Transporting, Mitochondrial Fo Complex, Subunit C2 (Subunit 9) (ATP5G2))

Alternative Name: ATP5G2 (ATP5G2 Products)

Synonyms: GB16842 antibody, 1810041M08Rik antibody, ATP5A antibody, ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) antibody, ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9) antibody, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) antibody, ATP5G2 antibody, Atp5g2 antibody

Background: ATP5G2 is a subunit of mitochondrial ATP synthase. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. ATP5G2 is one of three precursors of subunit c.This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. The protein encoded by this gene is one of three precursors of subunit c. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene has multiple pseudogenes.
Alias Symbols: ATP5A
Protein Interaction Partner: XRN1, TDP2, UBC, ATP13A2,
Protein Size: 141

Molecular Weight: 15 kDa

Gene ID: 517

NCBI Accession: NM_001002031, NP_001002031

UniProt: Q06055

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process