IRF4 antibody (Interferon Regulatory Factor 4) (Middle Region)

Details for Product anti-IRF4 Antibody No. ABIN2780429, Supplier: Log in to see
Antigen
  • IRF4
  • irf4
  • LSIRF
  • MUM1
  • NF-EM5
  • AI385587
  • IRF-4
  • Spip
  • si:ch73-170d1.2
  • interferon regulatory factor 4
  • Interferon regulatory factor 4
  • interferon regulatory factor 4a
  • melanoma associated antigen (mutated) 1
  • IRF4
  • irf4
  • LOC100223845
  • Irf4
  • irf4a
  • MUM1
Alternatives
anti-Human IRF4 antibody for Immunohistochemistry (Frozen Sections)
Epitope
Middle Region
28
8
7
6
6
5
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Guinea Pig, Horse (Equine), Human, Rat (Rattus)
138
48
24
4
4
4
4
4
4
3
2
2
2
2
1
Host
Rabbit
89
24
17
9
2
Clonality
Polyclonal
Conjugate
This IRF4 antibody is un-conjugated
3
2
2
1
1
1
1
1
Application
Western Blotting (WB)
120
53
36
30
19
16
10
4
3
3
3
3
1
Options
Supplier
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Supplier Product No.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human IRF4
Blocking Peptide Blocking peptide for this product available: ABIN978604
Sequence TAHVEPLLAR QLYYFAQQNS GHFLRGYDLP EHISNPEDYH RSIRHSSIQE
Predicted Reactivity Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Rat: 93%
Characteristics This is a rabbit polyclonal antibody against IRF4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name IRF4 (IRF4 Antibody Abstract)
Background IRF4 is a transcriptional activator. It binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter.It also binds the immunoglobulin lambda light chain enhancer, together with PU.1. IRF4 probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.
Alias Symbols: LSIRF, MUM1, NF-EM5
Protein Interaction Partner: UBC, STAT6, BCL6, TOP1, IRAK1, PRRC2B, YTHDC2, VPS35, PEG10, TLK2, CARM1, IKBKAP, ETV7, BATF, HOXB13, PROX1, HOXC11, FKBP4, SPIB, PRDM1, MYD88, TRAF2, NFATC2, SPI1,
Protein Size: 451
Molecular Weight 52 kDa
Gene ID 3662
NCBI Accession NM_002460, NP_002451
UniProt Q15306
Pathways Chromatin Binding
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 451 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Interferon Regulatory Factor 4 (IRF4) (Middle Region) antibody (ABIN2780429) WB Suggested Anti-IRF4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Product cited in: Han, Kraft, Nan, Guo, Chen, Qureshi, Hankinson, Hu, Duffy, Zhao, Martin, Montgomery, Hayward, Thomas, Hoover, Chanock, Hunter: "A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation." in: PLoS genetics, Vol. 4, Issue 5, pp. e1000074, 2008 (PubMed).

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