HMBOX1 antibody (N-Term)

Catalog No. ABIN2781213

Product Details anti-HMBOX1 Antibody

Target: HMBOX1 (Homeobox Containing 1 (HMBOX1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMBOX1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ETMSHYTDEP RFTIEQIDLL QRLRRTGMTK HEILHALETL DRLDQEHSDK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against HMBOX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HMBOX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 420 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMBOX1

Target: HMBOX1 (Homeobox Containing 1 (HMBOX1))

Alternative Name: HMBOX1 (HMBOX1 Products)

Synonyms: pbhnf antibody, hnf1la antibody, MGC81685 antibody, hmbox1 antibody, HNF1LA antibody, HOT1 antibody, PBHNF antibody, AI451877 antibody, AI604847 antibody, F830020C16Rik antibody, RGD1306787 antibody, zgc:114064 antibody, homeobox containing 1 S homeolog antibody, homeobox containing 1 antibody, homeobox containing 1 L homeolog antibody, homeobox containing 1a antibody, hmbox1.S antibody, HMBOX1 antibody, hmbox1.L antibody, Hmbox1 antibody, hmbox1a antibody

Background: HMBOX1 is located at the boundary of 8p12.3 and 8p21.1. HMBOX1 proteins are highly conserved in human, mouse, rat, chicken and Xenopus laevis. Functional HMBOX1::EGFP (enhanced green fluorescent protein) fusion protein revealed that HMBOX1 accumulated more in cytoplasm than in nucleus. HMBOX1 is a transcription repressor. Human HMBOX1 is widely expressed in 18 tissues, and it is highly expressed in pancreas. Hmbox1 is widely expressed in mouse pancreas and the expression of this gene can also be detected in pallium, hippocampus and hypothalamus.
Alias Symbols: PBHNF, HNF1LA
Protein Interaction Partner: FAM74A4, PKD1P1, FAM13C, TCEANC, RBMY2FP, ZMAT2, ZNF417, DYNLL2, ASB7, FRMD6, AEBP2, SFR1, REEP6, ZNF587, LNX1, FAM161A, SAP30L, HMBOX1, C20orf195, C8orf33, UBE2Z, MRPL11, CARD9, SH2D4A, CBX8, UBA6, FAM206A, ZNF581, MAGEH1, ZNF337, MORF4L1, FARS2, MRPL28,
Protein Size: 420

Molecular Weight: 47 kDa

Gene ID: 79618

NCBI Accession: NM_024567, NP_078843

UniProt: Q6NT76