HPRT1 antibody (Middle Region)

Catalog No. ABIN2783383

Product Details anti-HPRT1 Antibody

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Rabbit, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPRT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: STGDIKVIGG DDLSTLTGKN VLIVEDIIDT GKTMQTLLSL VRQYNPKMVK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HPRT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HPRT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 218 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HPRT1

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Alternative Name: HPRT1 (HPRT1 Products)

Synonyms: HGPRT antibody, HPRT antibody, C81579 antibody, HPGRT antibody, Hprt1 antibody, Hgprtase antibody, Hprt antibody, id:ibd1344 antibody, id:ibd5108 antibody, wu:fc10g09 antibody, zgc:56221 antibody, zgc:86608 antibody, hgprt antibody, hprt antibody, prtfdc1 antibody, hprt1 antibody, hprt1l antibody, zgc:55561 antibody, zgc:86771 antibody, hypoxanthine phosphoribosyltransferase 1 antibody, hypoxanthine guanine phosphoribosyl transferase antibody, hypoxanthine phosphoribosyltransferase 1 L homeolog antibody, phosphoribosyl transferase domain containing 1 antibody, HPRT1 antibody, Hprt antibody, Hprt1 antibody, hprt1 antibody, hprt1.L antibody, prtfdc1 antibody

Background: HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate.HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate (Keebaugh et al., 2007 [PubMed 16928426]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HGPRT, HPRT
Protein Interaction Partner: PRTFDC1, WDYHV1, ISCU, UBC, SDCBP, HPRT1, FUS, SUMO1, NEDD8, NME1-NME2, PSAT1, PTGES3, SNCA, PPID, MTAP, EIF6, GOT1, ANXA6, FAT3, APRT, CUL3, CUL5, EIF1B, MCC, HUS1, FANCA,
Protein Size: 218

Molecular Weight: 24 kDa

Gene ID: 3251

NCBI Accession: NM_000194, NP_000185

UniProt: P00492

Pathways: Ribonucleoside Biosynthetic Process