C4orf49 antibody (C-Term)

Catalog No. ABIN2784045

Product Details anti-C4orf49 Antibody

Target: C4orf49 (Chromosome 4 Open Reading Frame 49 (C4orf49))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C4orf49 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EAVTIDNDKD TTKNETSDEY AELEEENSPA ESESSAGDDL QEEASVGSEA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MGARP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MGARP

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C4orf49

Target: C4orf49 (Chromosome 4 Open Reading Frame 49 (C4orf49))

Alternative Name: MGARP (C4orf49 Products)

Synonyms: 4930583H14Rik antibody, AI195347 antibody, CESP-1 antibody, HUMMR antibody, Osap antibody, Qsap antibody, C4orf49 antibody, OSAP antibody, mitochondria localized glutamic acid rich protein antibody, mitochondria-localized glutamic acid-rich protein antibody, Mgarp antibody, MGARP antibody

Background: MGARP plays a role in the trafficking of mitochondria along microtubules. It regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. It participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. It also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology.
Alias Symbols: C4orf49, CESP-1, HUMMR, OSAP
Protein Interaction Partner: EGFR,
Protein Size: 240

Molecular Weight: 26 kDa

Gene ID: 84709

NCBI Accession: NM_032623, NP_116012

UniProt: Q8TDB4