EXOC5 antibody (N-Term)

Catalog No. ABIN2784822

Product Details anti-EXOC5 Antibody

Target: EXOC5 (Exocyst Complex Component 5 (EXOC5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOC5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ATKVCHLGDQ LEGVNTPRQR AVEAQKLMKY FNEFLDGELK SDVFTNSEKI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against EXOC5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOC5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 708 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOC5

Target: EXOC5 (Exocyst Complex Component 5 (EXOC5))

Alternative Name: EXOC5 (EXOC5 Products)

Synonyms: CG6159 antibody, Dmel\\CG6159 antibody, P71 antibody, Sec10 antibody, Sec10p antibody, dSec10 antibody, dsec10 antibody, SEC10L1 antibody, MGC80624 antibody, sec10l1 antibody, zgc:175220 antibody, HSEC10 antibody, PRO1912 antibody, SEC10 antibody, SEC10P antibody, AI447711 antibody, AI448003 antibody, Gm76 antibody, Sec10l1 antibody, exocyst complex component sec10 antibody, Secretory 10 antibody, exocyst complex component 5 antibody, exocyst complex component 5 L homeolog antibody, exocyst complex component sec10 antibody, Exocyst complex component 5 antibody, Sec10 antibody, EXOC5 antibody, exoc5.L antibody, exoc5 antibody, CpipJ_CPIJ009626 antibody, Tsp_08508 antibody, Tsp_12387 antibody, Exoc5 antibody, SEC10 antibody, sec-10 antibody

Background: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Alias Symbols: DKFZp666H126, HSEC10, PRO1912, SEC10, SEC10L1, SEC10P
Protein Interaction Partner: HDDC3, TXLNB, CCDC67, TTC23L, FRMD6, BRMS1L, CCDC102B, KXD1, RAB4B, RAB14, TNPO2, PYCARD, EDRF1, C9orf9, TXNL4A, EXOC5, RAB4A, PTK6, OAS1, MAGEA6, ENO2, BARD1, UBC, EGFR, ACTR3B, ADCK1, TBX21, SOX10, ICA1, CDH2, EXOC8, EXOC4, EXOC2, EXOC7, EXOC3, UBD, PRK
Protein Size: 708

Molecular Weight: 82 kDa

Gene ID: 10640

NCBI Accession: NM_006544, NP_006535

UniProt: O00471

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis