H1FOO antibody (Middle Region)
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- Target See all H1FOO Antibodies
- H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This H1FOO antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KAPKAGQGPN TKAAAPAKGS GSKVVPAHLS RKTEAPKGPR KAGLPIKASS
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against H1FOO. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human H1FOO
- Top Product
- Discover our top product H1FOO Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 346 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))
- Alternative Name
- H1FOO (H1FOO Products)
- Synonyms
- osH1 antibody, C86609 antibody, H1fo antibody, H1oo antibody, b4 antibody, RGD1566236 antibody, H1 histone family member O oocyte specific antibody, H1 histone family, member O, oocyte-specific antibody, H1 histone family member O oocyte specific S homeolog antibody, H1FOO antibody, H1foo antibody, h1foo.S antibody
- Background
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H1FOO may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. H1FOO is essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Alias Symbols: MGC50807, osH1
Protein Size: 346 - Molecular Weight
- 36 kDa
- Gene ID
- 132243
- NCBI Accession
- NM_153833, NP_722575
- UniProt
- Q8IZA3
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