CRISP1 antibody (N-Term)
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- Target See all CRISP1 Antibodies
- CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CRISP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ARIFSKYCDM TESNPLERRL PNTFCGENMH MTSYPVSWSS VIGVWYSEST
- Predicted Reactivity
- Human: 100%, Mouse: 77%, Rat: 77%
- Characteristics
- This is a rabbit polyclonal antibody against CRISP1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CRISP1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 249 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))
- Alternative Name
- CRISP1 (CRISP1 Products)
- Synonyms
- AEGL1 antibody, ARP antibody, CRISP-1 antibody, HSCRISP1D antibody, HSCRISP1G antibody, HUMARP antibody, AW324342 antibody, Aeg1 antibody, AEG antibody, crisp-1 antibody, cysteine rich secretory protein 1 antibody, cysteine-rich secretory protein 1 antibody, CRISP1 antibody, Crisp1 antibody
- Background
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Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. CRISP1 is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface.
Alias Symbols: AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP
Protein Size: 249 - Molecular Weight
- 27 kDa
- Gene ID
- 167
- NCBI Accession
- NM_001131, NP_001122
- UniProt
- P54107
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