RPSA/Laminin Receptor antibody (N-Term)
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- Target See all RPSA/Laminin Receptor (RPSA) Antibodies
- RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Sheep, Pig, Goat, Horse, Rabbit, Dog, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RPSA/Laminin Receptor antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QMKEEDVLKF LAAGTHLGGT NLDFQMEQYI YKRKSDGIYI INLKRTWEKL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against Rpsa. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product RPSA Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 295 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
- Alternative Name
- Rpsa (RPSA Products)
- Synonyms
- 37LRP antibody, 67LR antibody, LBP/p40 antibody, LRP/LR antibody, LamR antibody, rpsa antibody, LamR1 antibody, RPSA antibody, LAMBR antibody, LAMR1 antibody, LBP antibody, LRP antibody, NEM/1CHD4 antibody, SA antibody, lamR antibody, p40 antibody, 67kDa antibody, 67lr antibody, AL022858 antibody, Lamr antibody, Lamr1 antibody, Lamrl1 antibody, MLR antibody, P40 antibody, P40-3 antibody, P40-8 antibody, lamr1 antibody, zgc:55831 antibody, zgc:77824 antibody, DMRT1 antibody, 40S ribosomal protein SA antibody, 67kD laminin receptor antibody, ribosomal protein SA antibody, rssa antibody, rpsa antibody, RPSA antibody, Rpsa antibody, LOC100144340 antibody
- Background
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Rpsa is required for the assembly and/or stability of the 40S ribosomal subunit. It is also required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. It slso functions as a cell surface receptor for laminin. It plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. It may play a role in cell fate determination and tissue morphogenesis. It also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. It enables malignant tumor cells to penetrate laminin tissue and vessel barriers and activates precursor thymic anti-OFA/iLRP specific cytotoxic T cell. It may induce CD8 T-suppressor cells secreting IL-10.
Alias Symbols: 67 kDa, 67lr, AL022858, Lamr, Lamr1, Lamrl1, MGC117921, MGC118614, MLR, P40, P40-3, P40-8
Protein Interaction Partner: Eed, Rara, Rpgrip1l, Tcf3,
Protein Size: 295 - Molecular Weight
- 32 kDa
- Gene ID
- 16785
- NCBI Accession
- NM_011029, NP_035159
- UniProt
- P14206
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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