GNA12 antibody (Guanine Nucleotide Binding Protein (G Protein) alpha 12) (Middle Region)

Details for Product anti-GNA12 Antibody No. ABIN2785900, Supplier: Log in to see
Antigen
  • NNX3
  • RMP
  • gep
  • gna12
  • gna12l
  • AI414047
  • AI504261
  • Galpha12
  • guanine nucleotide binding protein (G protein) alpha 12
  • guanine nucleotide binding protein (G protein) alpha 12a
  • guanine nucleotide binding protein, alpha 12
  • GNA12
  • Gna12
  • gna12a
Epitope
Middle Region
17
15
4
3
3
2
2
2
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
49
25
23
5
4
4
4
4
4
3
3
3
1
1
1
Host
Rabbit
49
2
1
Clonality
Polyclonal
Conjugate
This GNA12 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
39
21
13
4
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human GNA12
Blocking Peptide Blocking peptide for this product available: ABIN977509
Sequence TFQLYVPALS ALWRDSGIRE AFSRRSEFQL GESVKYFLDN LDRIGQLNYF
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
Characteristics This is a rabbit polyclonal antibody against GNA12. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name GNA12 (GNA12 Antibody Abstract)
Background GNA12 belongs to the G-alpha family. G(12) subfamily. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Alias Symbols: MGC104623, MGC99644, NNX3, RMP, gep
Protein Interaction Partner: GNB3, ARAF, UBC, IL3RA, APP, LRRK2, SUMO1, PCK1, PPP2R1A, ARHGEF11, ARHGEF12, S1PR5, AKAP13, GNA13, GNA12, S1PR4, TSHR, NAPA, RASA2, PPP5C, TEC, BTK, CDH1, TBXA2R, F2R, PRKCA, HSP90AA1, GNB1, DRD5, CDH2, CDH15, ACTB, ARHGEF28, MAP3K5, RHOA, PRKCD, PRKCB,
Protein Size: 381
Molecular Weight 44 kDa
Gene ID 2768
NCBI Accession NM_007353, NP_031379
UniProt Q03113
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 381 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Immunohistochemistry (IHC) image for anti-GNA12 antibody (Guanine Nucleotide Binding Protein (G Protein) alpha 12) (Middle Region) (ABIN2785900) Rabbit Anti-GNA12 Antibody Catalog Number: ARP54813_P050 Formalin Fixed Paraffin Embe...
Western Blotting (WB) image for anti-GNA12 antibody (Guanine Nucleotide Binding Protein (G Protein) alpha 12) (Middle Region) (ABIN2785900) WB Suggested Anti-GNA12 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positiv...
Background publications Jeske, So, Kelemen, Sukor, Willys, Bulmer, Gordon, Duffy, Stowasser: "Examination of chromosome 7p22 candidate genes RBaK, PMS2 and GNA12 in familial hyperaldosteronism type II." in: Clinical and experimental pharmacology & physiology, Vol. 35, Issue 4, pp. 380-5, 2008 (PubMed).