GCET2 antibody (Middle Region)

Catalog No. ABIN2786263

Product Details anti-GCET2 Antibody

Target: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCET2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YSLLHMPSTD PRHARSPEDE YELLMPHRIS SHFLQQPRPL MAPSETQFSH

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GCET2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GCET2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 178 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GCET2

Target: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Alternative Name: GCET2 (GCET2 Products)

Synonyms: Gcet antibody, Gcet2 antibody, M17 antibody, M17-L antibody, GCAT2 antibody, GCET2 antibody, HGAL antibody, germinal center associated, signaling and motility antibody, germinal center associated signaling and motility antibody, germinal center-associated, signaling and motility antibody, Gcsam antibody, GCSAM antibody

Background: GCET2 is a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4.This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: GCAT2, HGAL, MGC40441, GCET2
Protein Interaction Partner: APPBP2, UBC,
Protein Size: 178

Molecular Weight: 21 kDa

Gene ID: 257144

NCBI Accession: NM_152785, NP_689998

UniProt: Q8N6F7