SERPINB2 antibody (Plasminogen Activator Inhibitor 2) (Middle Region)

Details for Product anti-SERPINB2 Antibody No. ABIN2786668, Supplier: Log in to see
Antigen
  • HsT1201
  • PAI
  • PAI-2
  • PAI2
  • PLANH2
  • LOC100101625
  • SERPINB2
  • Planh2
  • ovalbumin
  • Pai2a
  • serpin peptidase inhibitor, clade B (ovalbumin), member 2
  • plasminogen activator inhibitor 2
  • serine (or cysteine) peptidase inhibitor, clade B, member 2
  • SERPINB2
  • LOC100101625
  • Serpinb2
Alternatives
anti-Human SERPINB2 antibody for Immunofluorescence (fixed cells)
Epitope
Middle Region
9
5
5
5
5
4
4
4
4
3
3
3
2
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine)
112
33
28
4
3
3
2
2
2
2
1
Host
Rabbit
91
35
4
1
Clonality
Polyclonal
Conjugate
This SERPINB2 antibody is un-conjugated
6
6
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
102
46
35
28
26
13
9
9
4
3
3
3
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human SERPINB2
Blocking Peptide Blocking peptide for this product available: ABIN983572
Sequence GKIPNLLPEG SVDGDTRMVL VNAVYFKGKW KTPFEKKLNG LYPFRVNSAQ
Predicted Reactivity Cow: 86%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 85%, Sheep: 86%
Characteristics This is a rabbit polyclonal antibody against SERPINB2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SERPINB2 (SERPINB2 Antibody Abstract)
Background SERPINB2 inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Alias Symbols: HsT1201, PAI, PAI-2, PAI2, PLANH2
Protein Interaction Partner: UBC, APP, PRPF8, PSMB1, RBL2, RB1, IRF3, PLAU, SERPINB2,
Protein Size: 415
Molecular Weight 44 kDa
Gene ID 5055
NCBI Accession NM_002575, NP_002566
UniProt P05120
Pathways Autophagy
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 415 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-SERPINB2 antibody (Plasminogen Activator Inhibitor 2) (Middle Region) (ABIN2786668) WB Suggested Anti-SERPINB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Product cited in: Stutchbury, Al-Ejeh, Stillfried, Croucher, Andrews, Irving, Links, Ranson: "Preclinical evaluation of 213Bi-labeled plasminogen activator inhibitor type 2 in an orthotopic murine xenogenic model of human breast carcinoma." in: Molecular cancer therapeutics, Vol. 6, Issue 1, pp. 203-12, 2007 (PubMed).

Background publications Croucher, Saunders, Stillfried, Ranson: "A structural basis for differential cell signalling by PAI-1 and PAI-2 in breast cancer cells." in: The Biochemical journal, Vol. 408, Issue 2, pp. 203-10, 2007 (PubMed).