SERPINB2 antibody (Middle Region)

Catalog No. ABIN2786668

Product Details anti-SERPINB2 Antibody

Target: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Horse, Dog, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINB2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GKIPNLLPEG SVDGDTRMVL VNAVYFKGKW KTPFEKKLNG LYPFRVNSAQ

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 85%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against SERPINB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SERPINB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 415 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SERPINB2 antibody (ABIN2786668)

Stutchbury, Al-Ejeh, Stillfried, Croucher, Andrews, Irving, Links, Ranson: "Preclinical evaluation of 213Bi-labeled plasminogen activator inhibitor type 2 in an orthotopic murine xenogenic model of human breast carcinoma." in: Molecular cancer therapeutics, Vol. 6, Issue 1, pp. 203-12, (2007) (PubMed).

Target Details for SERPINB2

Target: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Alternative Name: SERPINB2 (SERPINB2 Products)

Synonyms: HsT1201 antibody, PAI antibody, PAI-2 antibody, PAI2 antibody, PLANH2 antibody, SERPINB2 antibody, Planh2 antibody, ovalbumin antibody, Pai2a antibody, serpin family B member 2 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 2 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 2 antibody, SERPINB2 antibody, Serpinb2 antibody

Target Type: Amino Acid

Background: SERPINB2 inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Alias Symbols: HsT1201, PAI, PAI-2, PAI2, PLANH2
Protein Interaction Partner: UBC, APP, PRPF8, PSMB1, RBL2, RB1, IRF3, PLAU, SERPINB2,
Protein Size: 415

Molecular Weight: 44 kDa

Gene ID: 5055

NCBI Accession: NM_002575, NP_002566

UniProt: P05120

Pathways: Autophagy