CDCA7L antibody (Middle Region)

Catalog No. ABIN2787158

Product Details anti-CDCA7L Antibody

Target: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA7L antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PPCRGICNCS YCRKRDGRCA TGILIHLAKF YGYDNVKEYL ESLQKELVED

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 90%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CDCA7L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDCA7L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 420 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDCA7L

Target: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Alternative Name: CDCA7L (CDCA7L Products)

Synonyms: ram2 antibody, MGC154777 antibody, BC006933 antibody, JPO2 antibody, R1 antibody, RAM2 antibody, RAPGEF5 antibody, cell division cycle associated 7 like antibody, cell division cycle associated 7 like L homeolog antibody, cell division cycle-associated 7-like protein antibody, CDCA7L antibody, cdca7l.L antibody, LOC100454683 antibody, Cdca7l antibody

Background: CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter.CDCA7L plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. CDCA7L is involved in apoptotic signaling pathways. CDCA7L may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Alias Symbols: DKFZp762L0311, JPO2, R1, RAM2
Protein Interaction Partner: KRTAP10-7, TRIM42, MORN3, BEND7, FAM9B, DEDD2, SSX2IP, ING5, TRAF3IP3, CEP70, CCDC33, CARD9, PRDM14, ZNF250, UTP3, CTNNBL1, ZNF821, CDCA7L, TFPT, ABT1, PRPF31, PPP1R16B, EIF4A3, STX11, UBL4A, TADA2A, NOP2, MFAP1, MDFI, LMO1, DAXX, BYSL, ANKRD11, SUV39H1,
Protein Size: 420

Molecular Weight: 46 kDa

Gene ID: 55536

NCBI Accession: NM_001127370, NP_001120842

UniProt: B3KTR5