CTF18 antibody (Middle Region)

Catalog No. ABIN2787289

Product Details anti-CTF18 Antibody

Target: CTF18 (CHTF18) (CTF18, Chromosome Transmission Fidelity Factor 18 Homolog (CHTF18))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Zebrafish (Danio rerio), Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTF18 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QALLLDALCL LLDILAPKLR PVSTQLYSTR EKQQLASLVG TMLAYSLTYR

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 93%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against CHTF18. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHTF18

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 975 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CTF18

Target: CTF18 (CHTF18) (CTF18, Chromosome Transmission Fidelity Factor 18 Homolog (CHTF18))

Alternative Name: CHTF18 (CHTF18 Products)

Synonyms: CHTF18 antibody, zgc:113153 antibody, MGC81266 antibody, 6030457M03Rik antibody, CTF18 antibody, Chl12 antibody, C16orf41 antibody, C321D2.2 antibody, C321D2.3 antibody, C321D2.4 antibody, CHL12 antibody, Ctf18 antibody, RUVBL antibody, chromosome transmission fidelity factor 18 antibody, CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) antibody, chromosome transmission fidelity factor 18 L homeolog antibody, chromosome transmission fidelity protein 18 homolog antibody, CTF18, chromosome transmission fidelity factor 18 antibody, Chtf18 antibody, CHTF18 antibody, chtf18 antibody, chtf18.L antibody, LOC726742 antibody, LOC100160476 antibody, LOC100433034 antibody, LOC100442428 antibody, LOC100632105 antibody, LOC100642927 antibody

Background: CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1, MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176], Bermudez et al., 2003 [PubMed 12930902]).
Alias Symbols: C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, Ctf18, RUVBL
Protein Interaction Partner: PCNA, RPA3, RPA2, RPA1, UBC, DSCC1, RFC2, SUMO2, MYC, DDX11, RFC4, RFC1, CHTF8, RFC3, SMC1A, RFC5, RAD21, HSP90AA1, HSPA4,
Protein Size: 975

Molecular Weight: 107 kDa

Gene ID: 63922

NCBI Accession: NM_022092, NP_071375

UniProt: Q8WVB6