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MED7 antibody (Middle Region)

MED7 Reactivity: Human, Mouse, Dog, Rabbit, Cow, Guinea Pig, Horse, Rat, Zebrafish (Danio rerio) WB, ChIP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787458
  • Target See all MED7 Antibodies
    MED7 (Mediator Complex Subunit 7 (MED7))
    Binding Specificity
    • 15
    • 10
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    Middle Region
    Reactivity
    • 50
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Human, Mouse, Dog, Rabbit, Cow, Guinea Pig, Horse, Rat, Zebrafish (Danio rerio)
    Host
    • 44
    • 6
    Rabbit
    Clonality
    • 46
    • 4
    Polyclonal
    Conjugate
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MED7 antibody is un-conjugated
    Application
    • 45
    • 24
    • 14
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    Sequence
    KRQRLETAER FQKHLERVIE MIQNCLASLP DDLPHSEAGM RVKTEPMDAD
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against MED7. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human MED7
    Top Product
    Discover our top product MED7 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 233 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MED7 (Mediator Complex Subunit 7 (MED7))
    Alternative Name
    MED7 (MED7 Products)
    Synonyms
    ARC34 antibody, CRSP33 antibody, CRSP9 antibody, 1110063B05Rik antibody, Crsp33 antibody, Crsp9 antibody, crsp9 antibody, wu:fd99d12 antibody, zgc:56241 antibody, crsp9-A antibody, med7-a antibody, mediator complex subunit 7 antibody, mediator complex subunit 7 L homeolog antibody, mediator complex subunit antibody, mediator complex subunit Med7 antibody, MED7 antibody, Med7 antibody, med7 antibody, med7.L antibody
    Background
    The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: CRSP33, CRSP9, MGC12284, ARC34
    Protein Interaction Partner: HAUS1, CDK8, CDK19, MED13, MED19, MED26, EPAS1, MED6, UBE2I, UL48, SUMO2, UBC, CTDP1, MED10, MED25, MED15, MED14, VDR, SREBF1, RELA, PARP1, ZSCAN1, TRIM15, RHOXF2, PCBD2, MED31, TRIM29, RBFOX2, IKBKG, LZTR1, PML, MED9, MED8, HGS, MED1, HNF4A, ESR2, ESR1,
    Protein Size: 233
    Molecular Weight
    27 kDa
    Gene ID
    9443
    NCBI Accession
    NM_004270, NP_004261
    UniProt
    O43513
    Pathways
    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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