FRS3 antibody (C-Term)

Catalog No. ABIN2787696

Product Details anti-FRS3 Antibody

Target: FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Dog, Horse, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRS3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: APGPTPHPVR SSDSYAVIDL KKTAAMSDLQ RALPRDDGAV RKTRHNSTDL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Frs3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Frs3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 492 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FRS3

Target: FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))

Alternative Name: Frs3 (FRS3 Products)

Synonyms: MGC82242 antibody, snt2 antibody, frs2b antibody, snt-2 antibody, frs2beta antibody, FRS2-beta antibody, FRS2B antibody, FRS2beta antibody, SNT-2 antibody, SNT2 antibody, 4930417B13Rik antibody, AI449674 antibody, Frs2beta antibody, Snt2 antibody, fibroblast growth factor receptor substrate 3 S homeolog antibody, fibroblast growth factor receptor substrate 3 antibody, frs3.S antibody, FRS3 antibody, frs3 antibody, Frs3 antibody

Background: Frs3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. It is involved in the activation of MAP kinases. Frs3 Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Alias Symbols: 4930417B13Rik, AI449674, Frs2beta, MGC25496, Snt2
Protein Interaction Partner: Bmpr2,
Protein Size: 492

Molecular Weight: 54 kDa

Gene ID: 107971

NCBI Accession: NM_144939, NP_659188

UniProt: Q91WJ0