SERPINA1 antibody (C-Term)

Catalog No. ABIN2787988

Product Details anti-SERPINA1 Antibody

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LTHDIITKFL ENEDRRSASL HLPKLSITGT YDLKSVLGQL GITKVFSNGA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SERPINA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SERPINA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 418 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SERPINA1 antibody (ABIN2787988)

Kam, Hennessy, Chua, Gan, Philp, Hon, Lai, Chan, Ong, Wong, Lim, Ling, Tan, Tan, Ho, Kon: "Characterization of the human gastric fluid proteome reveals distinct pH-dependent protein profiles: implications for biomarker studies." in: Journal of proteome research, Vol. 10, Issue 10, pp. 4535-46, (2011) (PubMed).

Koh, Rhee, Kang, Yang, You, Lee, Min, Kim, Nam, Kim: "Differential gene expression profiles of metastases in paired primary and metastatic colorectal carcinomas." in: Oncology, Vol. 75, Issue 1-2, pp. 92-101, (2008) (PubMed).

Target Details for SERPINA1

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Alternative Name: SERPINA1 (SERPINA1 Products)

Synonyms: AACT antibody, ACT antibody, GIG25 antibody, A1AT antibody, PI antibody, alpha-1-PI antibody, A1A antibody, AAT antibody, PI1 antibody, PRO2275 antibody, alpha1AT antibody, Pi antibody, Spi1 antibody, MGC64429 antibody, serpina1d antibody, Aps antibody, SERPINA3-5 antibody, serpin family A member 3 antibody, alpha-1-antiproteinase F precursor antibody, serpin family A member 1 antibody, alpha-1-antitrypsin antibody, calumenin antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antibody, SH2B adaptor protein 2 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog antibody, SERPINA3 antibody, LOC100008973 antibody, SERPINA1 antibody, LOC100328621 antibody, CALU antibody, Serpina1 antibody, serpina1.S antibody, serpina1 antibody, SPIA5 antibody, Sh2b2 antibody, Calu antibody, serpina1.L antibody

Background: Alpha-1-antitrypsin is a protease inhibitor, deficiency of which is associated with emphysema and liver disease. The protein is encoded by a gene (PI) located on the distal long arm of chromosome 14.
Alias Symbols: A1A, A1AT, AAT, MGC23330, MGC9222, PI, PI1, PRO2275, alpha1AT
Protein Interaction Partner: DERL1, DERL2, FN1, RCHY1, SSR1, SDC2, SMAD4, ECHS1, CANX, ATP5C1, GSDMB, VKORC1, ERLEC1, OS9, VCP, UBC, RAP2A, MIS12, DERL3, PRSS3, KLK5, MMP26, ADAMTS4, PRSS2, SERPINA1, PRSS1, MMP11, MMP7, PRTN3, KLK3, ELANE, CELA1, CTRB1, CTSG, LRP1, KLK13,
Protein Size: 418

Molecular Weight: 44 kDa

Gene ID: 5265

NCBI Accession: NM_001127706, NP_001121178

UniProt: P01009