Apelin Receptor antibody (N-Term)

Catalog No. ABIN2788292

Product Details anti-Apelin Receptor Antibody

Target: Apelin Receptor (APLNR)

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Horse, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apelin Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NGLVLWTVFR SSREKRRSAD IFIASLAVAD LTFVVTLPLW ATYTYRDYDW

Predicted Reactivity: Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against APLNR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human APLNR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 380 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Apelin Receptor

Target: Apelin Receptor (APLNR)

Alternative Name: APLNR (APLNR Products)

Synonyms: AGTRL1 antibody, APJ antibody, APJR antibody, HG11 antibody, Agtrl1 antibody, msr/apj antibody, Apj antibody, X-msr antibody, Xangio1 antibody, Xmsr antibody, agtrl1 antibody, angio1 antibody, apj antibody, apjr antibody, hg11 antibody, msr antibody, APLNR antibody, DKFZp469C1532 antibody, agtrl1-B antibody, agtrl1b antibody, Agtrl1a antibody, grn antibody, zgc:114063 antibody, APJa antibody, XAngio1 antibody, agtrl1-A antibody, agtrl1a antibody, aplnr-a antibody, aplnr-b antibody, x-MSR antibody, xAngio1 antibody, APLNR1 antibody, apelin receptor antibody, apelin receptor S homeolog antibody, apelin receptor b antibody, apelin receptor L homeolog antibody, APLNR antibody, Aplnr antibody, aplnr antibody, aplnr.S antibody, aplnrb antibody, aplnr.L antibody

Background: This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
Alias Symbols: AGTRL1, APJ, APJR, FLJ90771, FLJ96609, HG11, MGC45246
Protein Interaction Partner: APLN,
Protein Size: 380

Molecular Weight: 43 kDa

Gene ID: 187

NCBI Accession: NM_005161, NP_005152

UniProt: P35414