MCEE antibody (C-Term)

Catalog No. ABIN2788409

Product Details anti-MCEE Antibody

Target: MCEE (Methylmalonyl CoA Epimerase (MCEE))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCEE antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DSPIAGFLQK NKAGGMHHIC IEVDNINAAV MDLKKKKIRS LSEEVKIGAH

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MCEE. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MCEE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 176 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MCEE

Target: MCEE (Methylmalonyl CoA Epimerase (MCEE))

Alternative Name: MCEE (MCEE Products)

Synonyms: MGC89112 antibody, zgc:112343 antibody, MGC116480 antibody, GLOD2 antibody, 1110007A04Rik antibody, methylmalonyl-CoA epimerase antibody, methylmalonyl CoA epimerase antibody, methylmalonyl-CoA epimerase S homeolog antibody, MCEE antibody, mcee antibody, mcee.S antibody, Mcee antibody

Background: MCEE catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branched chain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result in methylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria.
Alias Symbols: GLOD2
Protein Interaction Partner: CMTM5, AGTRAP, APP,
Protein Size: 176

Molecular Weight: 19 kDa

Gene ID: 84693

NCBI Accession: NM_032601, NP_115990

UniProt: Q96PE7

Pathways: Monocarboxylic Acid Catabolic Process