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ROCK2 antibody (Middle Region)

ROCK2 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788813
  • Target See all ROCK2 Antibodies
    ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
    Binding Specificity
    • 16
    • 15
    • 9
    • 8
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 104
    • 66
    • 66
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Pig, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 98
    • 7
    • 1
    Rabbit
    Clonality
    • 95
    • 11
    Polyclonal
    Conjugate
    • 47
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ROCK2 antibody is un-conjugated
    Application
    • 74
    • 36
    • 27
    • 27
    • 17
    • 17
    • 17
    • 11
    • 9
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KNAEYQRKAD HEADKKRNLE NDVNSLKDQL EDLKKRNQNS QISTEKVNQL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against ROCK2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product ROCK2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1388 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
    Alternative Name
    ROCK2 (ROCK2 Products)
    Synonyms
    rocka-a antibody, xROK antibody, rock2 antibody, rok2 antibody, ROCK2 antibody, B230113H15Rik antibody, ROKalpha antibody, Rho-kinase antibody, Rock-II antibody, Rock2m antibody, mKIAA0619 antibody, ROCK-II antibody, ROK antibody, Rho-associated, coiled-coil containing protein kinase 2 L homeolog antibody, rho-associated, coiled-coil containing protein kinase 2a antibody, Rho associated coiled-coil containing protein kinase 2 antibody, Rho-associated, coiled-coil containing protein kinase 2 antibody, Rho-associated coiled-coil containing protein kinase 2 antibody, rock2.L antibody, rock2a antibody, ROCK2 antibody, Rock2 antibody
    Background
    The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
    Alias Symbols: KIAA0619, ROCK-II
    Protein Interaction Partner: UBC, FAM21A, RABGEF1, GPHN, KIAA0196, MTA2, ZW10, NHP2L1, LMNA, MAGEC1, ELAVL1, PPP1R12A, STAU1, RHOA, IKBKE, STK16, MBP,
    Protein Size: 1388
    Molecular Weight
    153 kDa
    Gene ID
    9475
    NCBI Accession
    NM_004850, NP_004841
    UniProt
    O75116
    Pathways
    Microtubule Dynamics, WNT Signaling, Tube Formation
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